Hypertension or preeclampsia contraindicates the use of which uterotonic?

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Multiple Choice

Hypertension or preeclampsia contraindicates the use of which uterotonic?

Hypertension and preeclampsia require avoiding drugs that sharply increase vascular tone. Methylergonovine is a potent vasoconstrictor that raises systemic blood pressure by constricting vascular smooth muscle. In women with HTN or preeclampsia, this can trigger a dangerous hypertensive crisis or cerebrovascular events, so it should not be used. Opt for uterotonics with minimal systemic vasoconstriction, such as oxytocin (first-line) and, if needed, misoprostol.

Hypertension and preeclampsia require avoiding drugs that sharply increase vascular tone. Methylergonovine is a potent vasoconstrictor that raises systemic blood pressure by constricting vascular smooth muscle. In women with HTN or preeclampsia, this can trigger a dangerous hypertensive crisis or cerebrovascular events, so it should not be used. Opt for uterotonics with minimal systemic vasoconstriction, such as oxytocin (first-line) and, if needed, misoprostol.

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